In each application, funding may be requested for a maximum of up to five years. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary.

Letters of Intent Receipt Date(s): April 27, 2011.
Application Due Date(s):  May 27, 2011.

With this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites grant applications that: (a) address the etiology and etiologic mechanisms of hepatocellular carcinoma (HCC); (b) propose development of animal models for HCC; (c) propose novel approaches to prevent HCC malignancy; (d) propose therapeutic or diagnostic tools for reliable prognostic indicators for HCC; and/or (e) develop therapeutic approaches to minimize morbidity and mortality associated with HCC in humans. The primary focus of the proposed projects must be on the basic biology, prevention, and/or treatment of liver cancer. Applications that are exclusively focused on population studies and epidemiology will not be supported in connection with this FOA.

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